How the microbiome impacts athletic performance.
When Dr. Tom Incledon joined me on Power Athlete Radio, we didn’t talk about sets and reps. We talked about bacteria. Specifically, the microbiome (the ecosystem of bacteria living inside your gut) and how it may be one of the most powerful performance variables we aren’t actively training.
For years, strength athletes have obsessed over macros, supplementation, programming, sleep metrics, heart rate variability — all important. But what if your limiting factor isn’t your program?
What if it’s your gut?

One Bacteria. 100+ Genes.
Tom laid out something that should make every serious athlete pause. A single bacterial strain (Lactobacillus rhamnosus GG) has been shown to regulate 100–110 genes in the human body. Genes directly tied to inflammation.
Inflammation is the hidden governor on performance. Too much and you get:
- Chronic soreness
- Joint pain
- Slower recovery
- Higher injury risk
- Compromised immune function
Too little and you don’t adapt. The microbiome helps regulate that balance.
If you’re deficient in key bacterial strains, your inflammatory response can spiral. You feel beat up longer. Recovery drags. Training frequency drops. But if your gut is robust and diverse? You recover faster. Adapt quicker. Miss fewer sessions.
That’s not fringe wellness talk. That’s performance leverage.

The Elite Athlete Microbiome
Researchers studying Olympic-level competitors found something interesting. Certain elite athletes possess bacterial strains not commonly found in the general population.
Read that again. Unique bacterial signatures.
The obvious question: Were they born that way? Or did years of high-level training, nutrition, and environmental exposure create that microbiome?
We don’t have the full answer yet. But we do know this: The microbiome adapts.
Just like muscle. Just like connective tissue. Just like the nervous system.
Which means it can likely be trained.
The New Performance Arms Race
There are now companies paying elite athletes for stool samples. Why? To map the bacterial ecosystems of high performers. They’re trying to determine:
- What strains correlate with endurance?
- What strains correlate with power output?
- Which bacteria reduce inflammatory markers?
- Which improve nutrient absorption?
If they can isolate those strains, the next step is obvious. Replication.
We’re entering an era where optimizing your microbiome may be as standard as optimizing protein intake.
And if you think this won’t become mainstream in elite sport, you’re underestimating how competitive the margins are at the highest levels.
You Don’t Adapt in the Gym. You Adapt in Recovery.
This is where it hits home for strength athletes.
Training is stress. Adaptation happens when you recover from that stress.
If your gut influences:
- Immune regulation
- Inflammation
- Nutrient absorption
- Hormonal signaling
Then it influences adaptation.
You can run the perfect program — head over to our program selector quiz to find yours now — but if your gut is inflamed and dysfunctional, you’re handicapping yourself.
The microbiome isn’t separate from performance. It’s upstream of it.
This Isn’t a Social Media Buzzword
“Gut health” has been hijacked by influencers selling detox teas and elimination protocols. That’s not what we’re talking about.
We’re talking about:
- Gene expression
- Inflammatory control
- Microbial diversity
- Performance sustainability
Dr. Incledon made it clear, this is not fringe science. It’s emerging physiology.
And if you care about longevity in training (if you want to lift heavy into your 40s, 50s, and beyond) ignoring the microbiome is like ignoring sleep.
You can get away with it for a while. But eventually, it catches up.
What This Means for You
You don’t need a lab analyzing your stool tomorrow. But you should start thinking differently about:
- Food quality
- Fiber intake
- Fermented foods
- Recovery habits
- Chronic stress
Your microbiome responds to:
- What you eat
- How you train
- How you sleep
- Your stress load
It’s not magic. It’s adaptation. The same principle that drives progressive overload applies internally.
The athletes who win long term are the ones who manage inflammation, recover efficiently, and stay durable. The microbiome may be one of the most overlooked levers in that equation.
And in a world where everyone is chasing marginal gains… Why would you ignore an organ system that can regulate over 100 genes tied to performance?
RELATED CONTENT
Pod: Ep 684: Jacked By Science w/ Dr Tom Incledon
Tagged: Gut / Gut Bacteria / Gut Biome / Recovery / inflammation / microbiome
AUTHOR
John
John Welbourn is CEO of Power Athlete and host of Power Athlete Radio. He is a 9 year starter and veteran of the NFL. John was drafted with the 97th pick in 1999 NFL Draft and went on to be a starter for the Philadelphia Eagles from 1999-2003, appearing in 3 NFC Championship games, and for starter for the Kansas City Chiefs from 2004-2007. In 2008, he played with the New England Patriots until an injury ended his season early with him retiring in 2009. Over the course of his career, John has started over 100 games and has 10 play-off appearances. He was a four year lettermen while playing football at the University of California at Berkeley. He graduated with a bachelor's degree in Rhetoric in 1998. John has worked with the MLB, NFL, NHL, Olympic athletes and Military. He travels the world lecturing on performance and nutrition and records his podcast, Power Athlete Radio, every week with over 800 episodes spanning 13 years. You can catch up with John as his personal blog, Talk To Me Johnnie, on social media @johnwelbourn or at Power Athlete Radio.
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